The Clone Wars - S1E22 - Hostage Crisis

When Anakin gives Padmé his lightsaber in "Hostage Crisis" to prove his love for her, he does so in such a way that, if it were activated, the blade would impale her:

To some degree, this foreshadows the events of Revenge of the Sith where Anakin's turn to the dark side causes Padmé to lose her will to live.  Here, he comes very close to injuring her fatally.

The Clone Wars - S1E22 - "Hostage Crisis"

3:23 - Anakin:  "When I finished constructing my lightsaber, Obi-Wan said to me, 'Anakin, this weapon is your life.'"  Obi-Wan tells him, "This weapon is your life" in Attack of the Clones too [21:59].